Clinical and demographic information collected on 140 patients with biopsy proven lupus nephritis (LN) included age, gender, presence of anti-double-stranded DNA antibodies (dsDNA), serum C3 complement levels (C3C), serum C4 complement levels (C4C), urine protein to creatinine ratio (UrPrCr), and estimated glomerular filtration rate (EGFR). The gene discussed is C3; the disease is lupus nephritis.