Although no changes in hepatic gluconeogenesis gene expression were observed between WT and Gkn1−/− mice, there were significantly decreased levels of IL1β and IL6 mRNA in Gkn1−/− suggesting that the resistance to steatosis was accompanied by reduced hepatic inflammation in Gkn1−/− mice (Fig. 4g,h). The gene discussed is IL6; the disease is steatosis.