Results in Supplementary Fig. 6 showed no obvious difference in expression of toll-like receptor signaling and interferon pathway components Irf3/7/9, Stat1, and Isg15 between Uhrf1+/+/ApcMin/+ and Uhrf1ki/ki/ApcMin/+ mice in either normal or tumor tissues. The gene discussed is UHRF1; the disease is neoplasm.