LGALS9 and COVID-19: The point of ROC curve related to the best sensitivity/specificity indicated that a level of plasma Gal-9 below 2,042 pg/ml separates HCs from COVID-19 patients with 94.96% sensitivity (95% confidence interval [CI] = 89.44% to 97.66%) and 94.92% specificity (95% CI: 86.08 to 98.61%) (Fig. 1F).