The top-ranked hyperacetylated and hypoacetylated DARs resided within the DLG2 (adjusted p = 9.8 × 10− 4) and PTPRH (adjusted p-value 9.0 × 10− 3) genes, respectively, both of which have been previously associated with PD [4, 56–58]. Here, DARS1 is linked to Parkinson disease.