In line with recent reports [21], we found that patients with SLE had a lower percentage of CD14+CD16- (88.49 ± 5.9 for SLE vs. 92.72 ± 2.59 for HD, p = 0.017) and a higher percentage of CD14loCD16++ (6.21 ± 3.1 for SLE vs. 3.74 ± 1.19 for HD, p = 0.017) than HD. The gene discussed is CD14; the disease is systemic lupus erythematosus.