In addition, 44 (Figure 23) exerted significantly stronger antiproliferative effects than arsenic trioxide (ATO) in Acute Promyelocytic Leukemia (APL) and ATO-resistant APL cell lines, whereas it has a negligible cytotoxic effect on non-cancerous cell lines, including normal CD34+ cells and BMSCs from APL patients. This evidence concerns the gene CD34 and acute promyelocytic leukemia.