AKT1 and cancer: The KEGG pathway analysis of all DEGs between ADP and UDP mainly included pathways in PI3K-Akt signaling pathway, proteoglycans in cancer, neuroactive ligand-receptor interaction, focal adhesion, protein digestion and absorption, cytokine-cytokine receptor interaction, ECM-receptor interaction, Hippo signaling pathway, and cGMP-PKG signaling pathway (p < 0.05, Figure 4E).