At 6 h after sepsis, plasma IL-6 levels were determined to be 40 ng/mL, as shown in Figure 3A. These mice were then randomly grouped as: injection of vehicle, MSCs on the SF nanofibers, or MSCs on the control surface—as shown in Figure 3B. Primed MSCs were trypsinized from either the SF nanofibers or the control surfaces, and administered through the tail veins of septic mice, with 106 cells per mouse. The gene discussed is IL6; the disease is Sepsis.