Proteomics analysis revealed that GSTP1 is overexpressed in cisplatin- and irinotecan-resistant glioma [88,89], fluorouracil (5-FU)- and cisplatin-resistant gastric cancer cells [90], doxorubicin-resistant prostate cancer cells [91], and adriamycin-resistant breast cancer cells [92]. This evidence concerns the gene GSTP1 and central nervous system cancer.