NR1H3 and pulmonary fibrosis: Contrary to these findings, Kurowska-Stolarska and colleagues showed that mice depleted in miR155 (miR155−/−) actually had exacerbated lung fibrosis following bleomycin treatment, and suggested that this was due to deregulation of the miR-155 target gene the liver X receptor (LXR)α in lung fibroblasts and macrophages [44].