HSD3B1 and Infertility: Upon our result, the molecular mechanism of FBN that induced infertility was summarized in the downregulation in steroidogenic and fertility-related gene expression, including CYP17A1 and cytochrome P450 17A1, KISS1, kisspeptin, STAR, Cyp11a1, cholesterol side-chain cleavage enzyme mRNA (P450SCC) Hsd3b1, 3-beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase type I, Cyp19, and cytochrome P450 aromatase.