CCL2 and nervous system disorder: Daidzein, a major active isoflavone, exhibits anti-inflammatory activity in neurological disorders through the inhibition of NO production in LPS-stimulated models, and it may cure neurological disorders by inhibiting the expression of proinflammatory cytokines, chemokines, interleukin-6 mRNA, and monocyte chemoattractant protein-1 [65,66,67].