Nascimento et al. (2019) observed favorable results in an experimental model of acute inflammation and tumor progression with the extract of the Arctium lappa plant, demonstrating that in addition to its direct effect on tumor cells, A. lappa extract suppresses the migration of neutrophils, which is correlated with lower levels of cytokines such as IL-6, IL-1 and TNF-α [27]. This evidence concerns the gene TNF and neoplasm.