Treatment goals for prolactinoma include: (i) suppression of excess prolactin secretion and reversal of its clinical consequences (such as infertility, decreased libido, and bone mass density); (ii) reduction of tumor size and relief of mass effect (such as vision deficit and headaches); (iii) preservation of remaining pituitary function; and (iv) prevention of disease progression and recurrence [17,32]. This evidence concerns the gene PRL and neoplasm.