In this study, we carried out a meta-analysis to quantitatively assess the correlation between tumor-infiltrating PDGFR-β+ fibroblasts and clinical outcomes in solid tumors, and found that high density of intratumoral PDGFR-β+ fibroblasts was remarkably associated with worse overall survival (OS) and disease-free survival (DFS) of patients. This evidence concerns the gene PDGFRB and neoplasm.