In this study, we noted that increased number of tumor-infiltrating PDGFR-β+ fibroblasts remarkably reduced OS (HR = 1.68, 95% CI 1.42 to 1.99, P < 0.001) in human solid tumors, with little heterogeneity being detected among included researches (I2 = 21.5%, P = 0.179) (Figure 1). The gene discussed is PDGFRB; the disease is neoplasm.