In contrast, ZBTB7C mRNA expression was significantly reduced in lung adenocarcinoma (LUAD), pheochromocytoma and paraganglioma (PCPG), prostate adenocarcinoma (PRAD), rectal adenocarcinoma (READ), stomach adenocarcinoma (STAD) and thyroid carcinoma (THCA) samples compared with that in normal samples. This evidence concerns the gene ZBTB7C and lung adenocarcinoma.