Compared with that in normal samples from TCGA, the expression of ZBTB7C mRNA in lung squamous cell carcinoma (LUSC), breast invasive carcinoma (BRCA), colon adenocarcinoma (COAD), head and neck squamous cell carcinoma (HNSC), kidney chromophobe (KICH), kidney renal clear cell carcinoma (KIRC), and kidney renal papillary cell carcinoma (KIRP) was increased. The gene discussed is ZBTB7C; the disease is squamous cell lung carcinoma.