In contrast, ZBTB7C mRNA expression was significantly reduced in lung adenocarcinoma (LUAD), pheochromocytoma and paraganglioma (PCPG), prostate adenocarcinoma (PRAD), rectal adenocarcinoma (READ), stomach adenocarcinoma (STAD) and thyroid carcinoma (THCA) samples compared with that in normal samples. The gene discussed is ZBTB7C; the disease is rectum adenocarcinoma.