ASPM and neoplasm: For the pathways distribution from the KEGG database (c2.cp.kegg.v7.0), ASPM, CENPF, and PRC1 shared three important tumor-associated terms (KEGG_CELL_CYCLE, KEGG_OOCYTE_MEIOSIS, and KEGG_SPLICEOSOME) in the top five significant pathways (Figure 11G–11I).