As expected, mutations in frequent drivers such as CREBBP, KMT2D,TNFRSF14 and RRAGC were more frequent among follicular lymphomas, those of MYC, CCND3 and ID3 prevailed among Burkitt lymphoma and those of BTG2, PIM1, SGK1 and SOCS1 were more frequent among DLBCL. The gene discussed is CREBBP; the disease is Burkitt lymphoma.