All acquired SAXS data including fits and models were deposited to SASBDB (WT: SASDLJ3, R12C: SASDLL3 and L68P: SASDLK3). SAXS = small-angle X-ray scattering, ASD = autism spectrum disorders, Rg = radius of gyration, WT = wild type, SPN = SHANK/ProSAP N-terminal, ARR = ankyrin repeat. The gene discussed is SPN; the disease is autism spectrum disorder.