YAP1 and hepatocellular carcinoma: The importance of YAP/TAZ in hepatocellularcarcinoma (HCC) is anticipated in view of the crucial role of YAP/TAZ in liver development (Lee et al. 2016), and the initiation of a ductular reaction (bile duct epithelial cell expansion) upon liver injury (Tschaharganeh et al. 2013; Yimlamia et al, 2014; Panciera et al. 2016; Planas-Paz et al, 2019; Pepe-Mooney et al. 2019).