However, CHD5 is located on chromosome 1p36.31, a region commonly deleted in monosomy 1p36, and CHD5 haploinsufficiency was hypothesized to contribute to the clinical features of this syndrome, which include neurodevelopmental deficits (intellectual disability with limited language ability), delayed growth, hypotonia, seizures, craniofacial and skeletal features, hearing and vision impairment, as well as cardiac anomalies (Shimada et al. 2015). The gene discussed is CHD5; the disease is Intellectual disability.