The results of WB analysis also verified these alterations which showed that further miR-188-5p inhibition could restore the inhibitions in the expression of cyclinD1, cyclinE1 and Bcl-2 and the promotions in the expression of cleaved caspase-3 and 9 and Bax in the MM cells induced by MALAT1 knockdown (Figure 8(c and d)). The gene discussed is CASP3; the disease is Miyoshi myopathy.