Some researches have reported that NR4A3 represents a tumour suppressor role in tumorigeneses such as lymphoma, breast cancer and gastric cancer by inhibiting cell viability and inducing cell apoptosis, which is hinting that NR4A3 embraces different characterize of biological functions upon specific pathogenesis of diseases.33, 34, 35, 36, 37. The gene discussed is NR4A3; the disease is breast carcinoma.