Nevertheless, the overall seroprevalence (anti-S1 and/or anti-N IgG) of 44% in our ICHD cohort is almost double the rate of laboratory-confirmed (by positive SARS-CoV-2 swab) COVID-19 cases in London reported to the UK Renal Association,95 confirming that asymptomatic disease in patients on dialysis is common and highlights the limitations of early diagnostic screening strategies. This evidence concerns the gene PSMD1 and COVID-19.