NSD2 and Rauch-Steindl syndrome: As a reflection of the distinct facial gestalt and the greatly different disease severity, especially concerning ID, of NSD2 deficiency and contiguous gene deletions leading to WHS, which may also be important for families’ and physicians' perception of the patients’ prognosis, the NSD2-related disorder may be named Rauch–Steindl syndrome after the delineators of this phenotype.8