Using in situ hybridization on a cancer patient tissue microarray, we detected distinct cytoplasmic MIR100HG signals in lung adenocarcinoma, higher expression in malignant melanoma, and even higher in glioma specimen (Supplementary Fig. S17b), reflecting the findings of the PanCancer Atlas cohorts (Supplementary Fig. S17a). The gene discussed is MIR100HG; the disease is central nervous system cancer.