Through evaluation of several independent cohorts of LMS patients, we demonstrated the prognostic value of GFPT2 expression in primary uterine tumors, we showed the consistency of GFPT2 expression in disease progression and found a possible association between GFPT2 expression and glucose uptake measured by 18F-FDG PET in primary LMS. Here, GFPT2 is linked to tumor of uterus.