On this day, memory impairments in rTg4510-FKBP52 mice were evident by significantly increased errors in locating the escape platform compared to rTg4510-GFP (p < 0.05), WT-GFP (p < 0.001), and WT-FKBP52 (p < 0.001) mice (Fig. 4c). This evidence concerns the gene FKBP4 and memory impairment.