In addition to this, FKBP52 can induce aggregation of multiple tau species including wild-type tau, P301L tau (contains a proline-to-leucine mutation at position 301 as found in frontotemporal dementia), and a Tau-F4 fragment (a tau truncation with strong microtubule binding)16–18. The gene discussed is MAPT; the disease is frontotemporal dementia.