The fibroblast growth factor 21 (FGF21) is an example of a protein with higher levels in the T2D patients18,19, and the results from the two assays support this observation with consistent higher level of FGF21 in the T2D patients compared to the healthy individuals (Fig. 2c) with a correlation across all samples of 0.96 (Spearman) and 0.97 (Pearson), respectively. The gene discussed is FGF21; the disease is type 2 diabetes mellitus.