Agnospheres derived from CUP adenocarcinomas (AS901, AS43, and AS67, Supplementary Table 1) and neuroendocrine carcinoma (N-AS47), which maintained in culture an epithelioid phenotype (Fig. 1a), did not display EMT TF or marker expression (Fig. 2c). The gene discussed is TF; the disease is neuroendocrine carcinoma.