Similarly, the olfactory bulb exhibited an important up-regulation in the expression of these genes (Fig. 6N), but in a different and delayed pattern compared to the nasal turbinates: whereas Cxcl10 was overexpressed throughout the infection, there was no change in Ifn-λ, and the increase in Il-6, Ifn-β and Il-1β gene expression was observed only from 4 dpi, with Il-1β remaining up-regulated up to 14 dpi. The gene discussed is IL6; the disease is infection.