The percentages of tissue IL-9-producing CD4(+) T cells in the sepsis group were significantly higher than that in the sepsis+sh-IL-9 group (1.02%±0.07% vs. 0.16%±0.01%, P < 0.001), whereas IL-9-producing CD4(+) T cell percentages significantly lower than that in the sepsis+IL-9 group (1.02%±0.07% vs. 1.57%±0.10%, P < 0.01). The gene discussed is IL9; the disease is Sepsis.