G6PD and G6PD deficiency: 40 We previously reported that the G6PD deficiency in Botswana based on the hemizygous male frequency was 2.30% (95% CI, 1.77–2.83), and that the overall frequency of G6PD-deficient genotype A (hemizygote and homozygote genotypes only) was 1.26% (95% CI, 0.86–1.66); these rates should be considered when deciding to implement the use of primaquine in the country.41P.