Further work up has to be focused on identifying all the possible risk factors including prothrombotic states like protein C, protein S, Anti thrombin III levels, Factor V Leiden mutation, sepsis screen, haemoglobin levels for polycythemia, and maternal and child blood sugar levels before labelling pulmonary artery thrombosis as spontaneous [3, 5]. The gene discussed is PROS1; the disease is polycythemia.