Single-cell RNAseq data suggests that the average expression of FDXR within the human neural retina is relatively low, for example, compared with SSBP1 (see Supplementary Table S4 for graphical illustration of both genes RNAseq data), defects of which similarly cause both optic atrophy and retinal degeneration.17 This evidence concerns the gene SSBP1 and Leber hereditary optic neuropathy.