Moreover, further characterization of the buff mouse line has shown significant motor learning deficits not common to HPS (Zhen & Li, 2015), while mutation of a human‐associated HPS gene in zebrafish (dtnbp1) caused pigmentation deficits but minimal effects on CNS acidification (Chen et al, 2018). Here, DTNBP1 is linked to Hermansky-Pudlak syndrome.