The genes and chromosomes that are commonly dysregulated in MM patients were also tested in these 114 patients [chromosome 1q21 amplification, 4p16.3 (FGFR3), 16q23 (MAF), IgH translocations, abnormal chromosome counts] to show the potential effects of these common genetic dysregulations in the background of TP53 abnormality. The gene discussed is FGFR3; the disease is Miyoshi myopathy.