Upon DNA damage, poly(ADP‐ribose) polymerase 1 (PARP1) localizes to DNA damage sites and its auto‐poly(ADP‐ribosyl)ation triggers the recruitment of several proteins, for example fused in sarcoma/translocated in sarcoma (FUS/TLS), ewing sarcoma (EWS) and TATA box‐binding protein‐associated factor 68 kDa (TAF15), also abbreviated as FET proteins [69]. Here, FUS is linked to sarcoma.