Investigators reviewed 168 patients who presented with a suspected fracture-related infection at 2 level I trauma centers examining the diagnostic accuracy of individual serum inflammatory markers (C-reactive protein, white blood cell count, and erythrocyte sedimentation rate) in defining infection.[5] Fracture-related infection was defined as a positive microbiology result from a surgically obtained tissue sample, and absence of infection was defined as absence of clinical infection symptoms at follow-up of at least 6 months. The gene discussed is CRP; the disease is infection.