In most cancers, NRP1 and NRP2 expression was found to be positively correlated with immune checkpoint genes (CD274, CTLA4, HAVCR2, LAG3, PDCD1, PDCD1LG2, SIGLEC15, and TIGIT) (Figures 5(a) and 5(b)). The gene discussed is PDCD1LG2; the disease is cancer.