IL2 and influenza: ProtequFlu (marketed by Boehringer Ingelheim, formerly Merial Animal Health) contains two modified live canarypox virus recombinants expressing the EIV hemagglutinin (HA) gene of two significantly important strains of circulating EIVs.ProtequFlu has been shown to generate significantly high IgGa and IgGb anti-influenza antibody titers pre-challenge, a long-term 6-month anamnestic IgGa and IgGb protective responses post challenge with several American lineages and induces a specific IFN-y and IL-2 mRNA expression (98, 99).