Furthermore, chronic inflammation, evidenced by increased C-Reactive protein (CRP), as well as interleukin (IL)-10, monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1α (MIP-1α) and matrix metalloproteinase (MMP)-9 was present in patients with CTEPH (71–73), indicating that chronic inflammatory processes may play a role in the microvasculopathy. The gene discussed is CCL2; the disease is chronic thromboembolic pulmonary hypertension.