EGFR and oropharynx squamous cell carcinoma: Another report showed that inhibition of the PERK–eIF2α-GRP94 signaling pathway silenced the epidermal growth factor receptor (EGFR) and then increased the radiosensitivity of both radiosensitive and radioresistant oropharyngeal squamous cell carcinoma (OSCC) cells (Zhang et al., 2018).