Representing the superfamily of detoxifying enzymes with overlapping biotransformational capacities toward xenobiotics, as well as endogenous reactive oxygen species (Wu and Dong, 2012), the role of glutathione transferases (GSTs) has been extensively studied in the development and progression of different cancers (Pljesa-Ercegovac et al., 2018). Here, HPGDS is linked to cancer.