Our data on the association of GSTO2*G variant allele with increased risk of PC are in line with previous findings on ovarian (Pongstaporn et al., 2006), breast (Xu et al., 2014), bladder (Djukic et al., 2015), and clear cell renal cell carcinoma (Radic et al., 2018). Here, GSTO2 is linked to pachyonychia congenita.