ROR2 and autosomal recessive Robinow syndrome: Accumulating evidence from Ror2-knockout mice and RRS patients suggests a significant role of ROR2 in the early formation of chondrocytes as well as the development and formation of bone (DeChiara et al., 2000; Takeuchi et al., 2000; Patton and Afzal, 2002; Schwabe et al., 2004; Weissenböck et al., 2019).