SIRT1 and steatosis: Resveratrol is defined as a SIRT1 activator and is described by many authors to increase autophagic flux and alleviate steatosis in many rodent models, including HFD, MCD, and genetic interventions thought to relieve ER stress and inflammation (Li et al., 2014; Ji et al., 2015; Zhang Y. et al., 2015; Ding et al., 2017; Milton-Laskibar et al., 2018).