Interestingly, glioma patients expressing the highest levels of UT and mainly UII mRNA had significantly shorter survival durations than cases with lower expressions; this prognostic cue can be associated with the strong expression of UII and UT in the hypoxic/vascular area of GBM samples, the positive correlation found between UII and UT expression, and the density of the abnormal vascularization. Here, UTS2 is linked to central nervous system cancer.