UTS2 and central nervous system cancer: Within the four groups of GBM along with the Verhaak classification (Verhaak et al., 2010), UTS2R (UT) and UTS2D (URP) were expressed in all groups of GBM, but importantly, UTS2 (UII) exhibited a net higher expression in the mesenchymal subgroup, suggesting that UII may be associated with glioma prognosis (Figure 2C).