In the present study, we characterized the expression of UII peptides and their receptor UT in a series of human glioma biopsies compared with normal brain tissue by immunohistochemistry and from transcriptome array analyses of gliomas from The Cancer Genome Atlas (TCGA) database as well as by quantitative-PCR (qPCR) in glioma cell lines. Here, UTS2 is linked to glioma.