Moreover, tumor genes including c-Myc, KLF15, and NRP1 were reported to be targeted by miR-376a, which may explain why the re-expression of CTC1 cannot fully rescue the miR-376a overexpression-induced defects (Yang et al., 2017; Wang et al., 2018; Zhang L. et al., 2019). The gene discussed is CTC1; the disease is neoplasm.