The most common mutations involved in prostate cancer include BRCA1/2; ATM (odds ratio (OR) = 2.18), HoxB13 (OR = 3.23), genes involved in repairing mismatched genes and genes associated with Lynch Syndrome (OR = 4.87), and CHEK2 (OR = 1.98) (29). The gene discussed is HOXB13; the disease is Familial prostate cancer.